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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK1
All Species:
29.09
Human Site:
Y14
Identified Species:
49.23
UniProt:
O00141
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00141
NP_001137148.1
431
48942
Y14
A
A
K
G
T
L
T
Y
S
R
M
R
G
M
V
Chimpanzee
Pan troglodytes
XP_518751
605
68702
S100
S
P
R
R
P
P
K
S
S
Q
V
R
R
W
I
Rhesus Macaque
Macaca mulatta
XP_001102277
637
72261
R202
E
M
Q
G
A
L
A
R
A
R
L
E
S
L
L
Dog
Lupus familis
XP_849801
431
48950
Y14
A
A
R
G
A
L
T
Y
S
R
M
R
G
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVC6
431
48910
Y14
A
A
R
S
T
L
T
Y
S
R
M
R
G
M
V
Rat
Rattus norvegicus
Q06226
430
48909
Y14
A
A
R
S
T
L
T
Y
S
R
M
R
G
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507569
431
48976
Y14
A
S
G
P
T
L
T
Y
S
K
M
R
G
M
V
Chicken
Gallus gallus
Q6U1I9
432
48872
Y15
A
S
G
P
A
L
T
Y
S
K
M
R
G
M
V
Frog
Xenopus laevis
Q6GLY8
434
49082
Y16
A
G
A
S
T
L
T
Y
S
K
M
R
G
M
V
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Y16
V
S
A
P
D
L
T
Y
S
K
T
R
G
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
P75
P
S
R
T
S
A
A
P
T
H
D
S
G
T
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q2PJ68
463
54273
F53
F
E
E
Y
E
R
F
F
T
T
E
K
D
M
I
Sea Urchin
Strong. purpuratus
XP_001192139
440
49530
G14
G
A
D
L
K
L
P
G
K
K
L
F
G
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P12688
680
76461
R171
A
L
I
A
Q
L
S
R
V
Q
I
K
N
Q
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.7
66.2
97.6
N.A.
96.5
96.9
N.A.
95.3
95.1
88.9
86.6
N.A.
34.7
N.A.
47
62.7
Protein Similarity:
100
70.2
67.1
99
N.A.
98.6
98.6
N.A.
98.3
97.2
94.2
92.8
N.A.
47.9
N.A.
63.5
75
P-Site Identity:
100
13.3
20
86.6
N.A.
86.6
86.6
N.A.
73.3
66.6
73.3
46.6
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
46.6
53.3
93.3
N.A.
93.3
93.3
N.A.
86.6
80
80
66.6
N.A.
40
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
36
15
8
22
8
15
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
0
8
0
8
0
0
% D
% Glu:
8
8
8
0
8
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% F
% Gly:
8
8
15
22
0
0
0
8
0
0
0
0
72
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
15
% I
% Lys:
0
0
8
0
8
0
8
0
8
36
0
15
0
0
0
% K
% Leu:
0
8
0
8
0
79
0
0
0
0
15
0
0
15
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
50
0
0
58
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% N
% Pro:
8
8
0
22
8
8
8
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
15
0
0
0
8
0
% Q
% Arg:
0
0
36
8
0
8
0
15
0
36
0
65
8
0
0
% R
% Ser:
8
29
0
22
8
0
8
8
65
0
0
8
8
0
0
% S
% Thr:
0
0
0
8
36
0
58
0
15
8
8
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
8
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _